TABLE 4.
Prevalence of C. pneumoniae in monosymptomatic MS patients
| Patient | Age (yr) | Gender | CSF characteristics
|
Initial eventa | IgG indexb | OCc bands | Brain MRI resultsd | Cervical cord MRI results | PCR assay results
|
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| VUMCe
|
USF with MOMP primerf | ||||||||||||
| Cell count (no. of cells/μl) | Protein concn (mg/dl) | Glucose concn (mg/dl) | VU-MOMP | Tong and Sillis | |||||||||
| 1 | 27 | M | 21 | 59 | 53 | SC | 0.55 | − | Normal | Single T2 lesion | + | − | − |
| 2 | 32 | M | 10 | 38 | 58 | SC | 1.23 | − | Normal | Two T2 lesions | + | + | + |
| 3 | 42 | M | 3 | 86 | 70 | SC | 0.51 | − | Normal | Enhancing Lesion | − | − | − |
| 4 | 27 | F | 0 | 13 | 51 | ON | 0.46 | − | Normal | Normal | + | − | + |
| 5 | 38 | F | 1 | 24 | 64 | BS | 0.5 | − | Two T2 PV lesions | Normal | − | − | − |
| 6 | 45 | F | 0 | 23 | 50 | SC | 0.99 | + | Normal | Enhancing Lesion | + | + | + |
| 7 | 52 | M | 7 | Unknown | 71 | ON | 0.61 | − | Three PV lesions | NDg | − | − | − |
| 8 | 34 | F | 1 | 50 | 55 | ON | 0.6 | − | Multiple PV lesions | ND | − | − | + |
| 9 | 39 | F | 1 | 43 | 60 | BS | 0.39 | − | Multiple PV lesions | ND | − | + | ND |
| 10 | 33 | F | 1 | 56 | 57 | BS | 0.45 | + | Multiple PV lesions | Normal | − | − | − |
| 11 | 31 | F | 9 | 49 | 62 | ON | 1.41 | + | Single enhancing lesions | Single T2 lesion | + | + | + |
| 12 | 28 | F | 2 | 32 | 54 | ON | 0.74 | + | Normal | Single T2 lesion | − | − | + |
| 13 | 57 | F | 1 | 15 | 53 | SC | ND | + | Brian Normal | ND | − | ND | ND |
| 14 | 47 | F | 2 | 52 | 52 | BS | ND | + | Single T2 lesion Pons | ND | − | ND | ND |
| 15 | 42 | F | 21 | 26 | 65 | SC | ND | − | NSWM abnormal | ND | − | ND | ND |
| 16 | 41 | F | 1 | 21 | 65 | BS | ND | + | 3 NSWM lesions | ND | + | ND | ND |
| 17 | 25 | F | 0 | 27 | 59 | BS | ND | + | 4 NSWM lesions | ND | + | ND | ND |
Abbreviation for locations of initial events: SC, spinal cord; ON, optic nerve; BS, brain stem.
IgG, immunoglobulin G.
OC, oligoclonal.
PV, periventricular; NSWM, nonspecific white matter.
The total numbers of samples positive were 7 and 4 with the VU-MOMP and Tong and Sillis primers, respectively.
The total number of samples positive was 2.
ND, not done.