Table 3.

Logistic regression analysis of RCC risk according to genotype.

SNPs	Genetic model	OR (95% CI)	p-value
rs1049380 (ITPR2)	Codominant
	T/T	Ref.
	G/T	1.21 (0.80–1.82)	0.392
	G/G	0.60 (0.26–1.41)	0.238
	Dominant
	T/T	Ref.
	G/T + G/G	1.08 (0.73–1.61)	0.705
	Recessive
	T/T + G/T	Ref.
	G/G	0.56 (0.24–1.29)	0.172
rs10771279 (ITPR2)	Codominant
	T/T	Ref.
	C/T	0.81 (0.53–1.24)	0.326
	C/C	0.42 (0.22–0.80)	0.009
	Dominant
	T/T	Ref.
	C/T + C/C	0.70 (0.46–1.05)	0.085
	Recessive
	T/T + C/T	Ref.
	C/C	0.48 (0.27–0.87)	0.479
rs4903064 (DPF3)	Codominant
	T/T	Ref.
	C/T	1.38 (0.90–2.09)	0.131
	C/C	2.55 (1.22–5.48)	0.013
	Dominant
	T/T	Ref.
	C/T + C/C	1.52 (1.02–2.27)	0.037
	Recessive
	T/T + C/T	Ref.
	C/C	2.22 (1.08–4.56)	0.030
rs7579899 (EPAS1)	Codominant
	G/G	Ref.
	A/G	1.17 (0.76–1.79)	0.486
	A/A	1.92 (1.08–3.39)	0.025
	Dominant
	G/G	Ref.
	A/G + A/A	1.33 (0.90–1.99)	0.151
	Recessive
	G/G + A/G	Ref.
	A/A	1.78 (1.05–3.02)	0.033
rs35252396 (PVT1)	Codominant
	AC/AC	Ref.
	AC/CG	1.27 (0.80–2.00)	0.319
	CG/CG	1.37 (0.79–2.36)	0.264
	Dominant
	AC/AC	Ref.
	AC/CG + CG/CG	1.29 (0.84–1.98)	0.240
	Recessive
	AC/AC + AC/CG	Ref.
	CG/CG	1.16 (0.73–1.84)	0.481

OR are adjusted for age and sex.

p-values <0.05 are shown in italics. p-values <0.01 (Bonferroni-corrected significance) are shown in bold.