Table 2.
Participant kidney parameters by ART regimen
| Variable | TDF/DTG N = 367 | Other DTG-based* N = 116 | p-value |
|---|---|---|---|
| Serum creatinine Mean (SD) | 0.68 (0.15) | 0.59 (0.14) | <0.001 |
| eGFR serum creatinine (SD) | 118.8 (19.3) | 113.9 (20.1) | 0.32 |
| eGFR serum creatinine | |||
| > 90ml/min | 317 (87.3) | 103 (89.6) | 0.52 |
| < 90ml/min | 46 (12.7) | 12 (10.4) | |
| Cystatin C Mean(SD) | 0.81 (0.13) | 0.81 (0.12) | 0.78 |
| eGFR cystatin C (SD) | 114.2 (15.2) | 116.5 (15.3) | 0.15 |
| eGFR cystatin C | |||
| Above 90ml/min | 212 (58.4) | 60 (52.2) | 0.47 |
| Below 90ml/min | 151 (41.6) | 55 (47.8) | |
| Albumin creatinine ratio | |||
| Below 30mg/g | 328 (90.4) | 100 (87.0) | 0.29 |
| Above 30mg/g | 35 (9.6) | 15 (13.0) | |
| Proteinuria | |||
| Negative | 263 (71.7) | 81 (69.8) | 0.70 |
| Positive | 104 (28.3) | 35 (30.2) | |
*
Regimens with either abacavir or zidovudine together with lamivudine and dolutegravir.