Table 1.
Training cohort characteristics
| Characteristic | Overall, N = 9,543 | Training, N = 7,631 | Internal validation, N = 956 | Internal testing, N = 956 | p-value |
|---|---|---|---|---|---|
|
| |||||
| Age | 65 (56, 73) | 64 (56, 73) | 66 (57, 75) | 65 (57, 73) | 0.001 |
| Sex male | 5,023 (53%) | 4,014 (53%) | 504 (53%) | 505 (53%) | >0.9 |
| BMI | 29 (26, 34) | 29 (26, 34) | 30 (26, 34) | 29 (25, 34) | 0.8 |
| Hypercholesterolemia | 5,253 (56%) | 4,149 (55%) | 557 (59%) | 547 (58%) | 0.013 |
| Smoking | 1,376 (15%) | 148 (16%) | 1,076 (14%) | 152 (16%) | 0.2 |
| Hypertension | 6,146 (65%) | 4,878 (65%) | 638 (68%) | 630 (67%) | 0.07 |
| Diabetes | 2,519 (27%) | 1,991 (26%) | 265 (28%) | 263 (28%) | 0.4 |
| Post - PCI | 972 (10%) | 760 (10%) | 97 (10%) | 115 (12%) | 0.13 |
| Post - CABG | 396 (4.4%) | 316 (4.4%) | 41 (4.6%) | 39 (4.3%) | >0.9 |
| History of CAD | 1,240 (13%) | 977 (13%) | 119 (13%) | 144 (15%) | 0.13 |
| CAC score | 54 (0, 481) | 43 (0, 503) | 99 (1, 398) | 100 (1, 398) | <0.001 |
| CAC score category | <0.001 | ||||
| CAC = 0 | 3,214 (34%) | 2,736 (36%) | 239 (25%) | 239 (25%) | |
| CAC 1–100 | 2,112 (22%) | 1,634 (21%) | 239 (25%) | 239 (25%) | |
| CAC 101–400 | 1,588 (17%) | 1,110 (15%) | 239 (25%) | 239 (25%) | |
| CAC >400 | 2,629 (28%) | 2,151 (28%) | 239 (25%) | 239 (25%) | |
| ECG-gating | 1,827 (19%) | 1,431 (19%) | 212 (22%) | 184 (19%) | 0.04 |
Statistics presented: median (inter quartile range), n (%); Abbreviations: BMI – body mass index; CABG – coronary artery bypass grafting, CAC – coronary artery calcification; CAD – coronary artery disease; PCI -percutaneous coronary intervention