Table 2.
External cohort characteristics
| Characteristic | Overall, N = 4,331 | No CAC scan available, N = 1,594 | With available CAC scan, N = 2,737 | p-value |
|---|---|---|---|---|
|
| ||||
| Age | 71 (64, 79) | 73 (65, 80) | 70 (63, 78) | <0.001 |
| Male | 2,503 (58%) | 1,121 (70%) | 1,382 (50%) | <0.001 |
| BMI | 27 (24, 32) | 27 (24, 31) | 28 (24, 32) | 0.001 |
| Hypercholesterolemia | 2,910 (67%) | 1,239 (78%) | 1,671 (61%) | <0.001 |
| Smoking | 320 (7.4%) | 106 (6.6%) | 214 (7.8%) | 0.2 |
| Hypertension | 3,368 (78%) | 1,334 (84%) | 2,034 (74%) | <0.001 |
| Diabetes | 1,431 (33%) | 582 (37%) | 849 (31%) | <0.001 |
| Post - PCI | 978 (23%) | 869 (55%) | 109 (4.0%) | <0.001 |
| Post - CABG | 467 (11%) | 455 (29%) | 12 (0.4%) | <0.001 |
| MFR | 2.36 (1.81, 2.98) | 2.14 (1.62, 2.80) | 2.45 (1.93, 3.07) | <0.001 |
| SDS | 0 (0, 2) | 1 (0, 4) | 0 (0, 1) | <0.001 |
| History of CAD | 1,443 (33%) | 208 (76%) | 235 (8.6%) | <0.001 |
| Clinical CAC score | 0 (0, 220) | - | 106 (0, 523) | <0.001 |
| CAC score category | <0.001 | |||
| CAC = 0 | 685 (25%) | - | 685 (25%) | |
| CAC 1–100 | 662 (24%) | - | 662 (24%) | |
| CAC 101–400 | 586 (21%) | - | 586 (21%) | |
| CAC >400 | 804 (29%) | - | 804 (29%) | |
Statistics presented: median (inter quartile range), n (%); Abbreviations: BMI – body mass index; CABG – coronary artery bypass grafting, CAC – coronary artery calcification; CAD – coronary artery disease; PCI -percutaneous coronary intervention, MFR – myocardial flow rate, SDS – summed difference score