Figure 2. Uev1A protects against the nurse cell death induced by direct overexpression of Ras^G12V.

(A, C, and F) Representative samples (DAPI staining). (B) Molecular information of the uev1a^Δ1 and uev1a^Δ2 mutations. The red dashed lines represent nucleotide deletions. (D and G) Quantification data. 30 ovaries from 3-day-old flies were quantified for each genotype. Statistical significance was determined using t test (groups = 2) or one-way ANOVA (groups>2): **** (p<0.0001). (E) Protein sequence alignment of Uev1A, UBE2V1, and UBE2V2. It was performed using CLUSTALW and ESPript 3.0 software.

Figure 2—figure supplement 1. Uev1A protects against Yki^3SA-induced nurse cell death.

(A) Representative ovaries (DAPI staining). The red arrows denote degrading egg chambers. Scale bars: 200 μm. (B) Quantification data. 30 ovaries from 7-day-old flies were quantified for each genotype. Statistical significance was determined using t test: * (p<0.05) and **** (p<0.0001).