Table 2.
Neuropsychological profile (mean values and standard deviations) of CU and SCD groups at baseline
| CU (N = 139) | SCD (N = 36) | ANCOVA a | p | |
|---|---|---|---|---|
| Global Cognitive Functioning | ||||
| MMSE screening | 28.64 (1.32) | 28.03 (1.71) | F(3,171 = 0.959 | .329 |
| CAMCOG-R total score | 94.63 (6.43) | 89.94 (6.51) | F(3,171) = 4.208 | .042* |
| Memory | ||||
| Memory-CAMCOG-R subscale | 22.69 (2.47) | 21.16 (2.04) | F(3,171) = 3.495 | .063 |
| Immediate total-CVLT | 52.74 (9.17) | 48.83 (11.09) | F(3,171) = 0.001 | .974 |
| Short-term delayed recall CVLT | 10.94 (2.73) | 9.69 (3.00) | F(3,171) = 0.068 | .794 |
| Long-term delayed recall CVLT | 11.87 (2.64) | 10.63 (2.58) | F(3,171) = 0.233 | .630 |
| Attention and Processing Speed | ||||
| TMT-A (in seconds)b | 47.03 (19.95) | 52.11 (19.79) | F(3,171) = 0.750 | .388 |
| Attention-CAMCOG-R subscale | 7.79 (1.49) | 7.75 (1.20) | F(3,171) = 0.032 | .858 |
| Executive Functioning | ||||
| TMT-B (in seconds)b | 123.45 (70.57) | 147.86 (70.33) | F(3,171) = 0.449 | .504 |
| Phonological fluency (initiated by p-letter) | 14.78 (5.45) | 11.86 (4.46) | F(3,171) = 0.950 | .331 |
| Executive-CAMCOG-R subscale | 21.89 (4.06) | 18.44 (4.56) | F(3,171) = 0.5.841 | .017* |
| Language | ||||
| Language-CAMCOG-R subscale | 27.38 (1.96) | 26.00 (2.16) | F(3,171) = 3.615 | .059 |
| Semantic fluency (animals) | 20.00 (5.53) | 16.27 (4.14) | F(3,171) = 4.119 | .044* |
| BNT-60 item | 51.66 (7.21) | 47.75 (6.32) | F(3,171) = 1.999 | .159 |
aANCOVAs were controlled for participant age and years of education.
bTotal score > 300 s = missing/not applicable.
Note: Significance was set at *p < .05.
BNT = Boston Naming Test; CAMCOG-R = Cambridge Screening Test Revised; CU = cognitively unimpaired; CVLT = California Verbal Learning Test; MMSE = Mini-Mental State Examination; SCD = subjective cognitive decline; TMT = Trail Making Test. Significant p values in bold.