Table 3. Results of turbidity changes in solutions.
| Drug | Turbidity/NTU AVG±SD (change) |
|||
|---|---|---|---|---|
| 0 hour | 1 hour | 2 hour | 4 hour | |
| Tigecycline(1 mg/mL)A1 | 0.103±0.003 | 0.113±0.004 (0.010) | 0.124±0.005 (0.021) | 0.116±0.002 (0.013) |
| Tigecycline(0.5 mg/mL)A2 | 0.082±0.008 | 0.097±0.015 (0.015) | 0.108±0.001 (0.026) | 0.104±0.004 (0.022) |
| Metronidazole and sodium chloride injectionB | 0.132±0.002 | 0.115±0.007 (−0.017) | 0.101±0.004 (−0.031) | 0.092±0.003 (−0.040) |
| MeropenemC | 0.104±0.008 | 0.09±0.003 (−0.014) | 0.096±0.003 (−0.008) | 0.092±0.003 (−0.012) |
| Imipenem and cilastatinD | 0.174±0.005 | 0.168±0.002 (−0.006) | 0.169±0.001 (−0.005) | 0.151±0.002 (−0.023) |
| Fosfomycin sodiumE | 0.199±0.006 | 0.185±0.006 (−0.014) | 0.162±0.006 (−0.037) | 0.152±0.003 (−0.047) |
| AztreonamF | 0.650±0.002 | 0.670±0.016 (0.020) | 0.676±0.003 (0.026) | 0.635±0.003 (−0.015) |
| VancomycinG | 0.186±0.002 | 0.181±0.003 (−0.005) | 0.201±0.004 (0.015) | 0.197±0.004 (0.011) |
| CAZ-AVI H | 0.074±0.009 | 0.079±0.003 (0.005) | 0.079±0.008 (0.005) | 0.078±0.007 (0.004) |
| Calcium chloride with composite potassium hydrogen phosphateI | 26.390±0.181 | 102.23±5.261 (75.840) | – | – |
A1-G: the combinations of CAZ-AVI with selected drugs separately; H: negative control, 25 mg/ml CAZ-AVI in NS; I: positive control, calcium chloride with composite potassium in NS; J: positive control, 10 μm latex particles reference material; K: positive control, 25 μm particle count reference material; N: Tyndall negative; P: Tyndall positive.