Table 4.

Results of subgroup analysis stratified by CTI and glycemic status

CTI	Normoglycemia		Prediabetes		Diabetes		P for interaction
	CTI ≤ 8.45	CTI > 8.45	CTI ≤ 8.45	CTI > 8.45	CTI ≤ 8.45	CTI > 8.45
Female	1(Ref.)	1.01(0.70–1.46)	1.07(0.61–1.55)	1.33(0.99–1.80)	1.18(0.82–1.72)	1.41(0.86–2.30)	0.298
Male	1(Ref.)	1.27(0.85–1.87)	0.98(0.70–1.38)	1.45(1.09–1.93–2.55)	1.39(1.03–1.87)	1.76(1.26–2.47)
BMI < 30	1(Ref.)	1.18(0.88–1.60)	1.08(0.80–1.46)	1.38(0.97–1.97)	1.36(1.02–1.81)	1.40(1.07–1.84)	0.176
BMI ≥ 30	1(Ref.)	1.65(1.03–3.12)	1.03(0.55–1.92)	1.62(0.86–3.05)	1.76(1.07–2.87)	1.89(1.20–2.96)
Age < 65	1(Ref.)	0.82(0.26–2.60)	0.96(0.19–4.96)	1.63(0.39–6.88)	1.62(0.51–5.10)	2.46(0.97–6.23)	0.973
Age ≥ 65	1(Ref.)	1.36(1.00–1.86)	1.00(0.76–1.31)	1.48(1.19–1.84)	1.34(1.06–1.70)	1.59(1.23–2.05)
Smoking	1(Ref.)	2.31(0.83–6.46)	1.08(0.28–4.18)	2.72(1.07–6.89)	2.80(1.18–6.61)	2.95(1.15–7.62)	0.655
No smoking	1(Ref.)	0.87(0.48–1.59)	1.05(0.70–1.18)	1.08(0.58–2.00)	1.22(0.81–1.85)	1.36(0.87–2.13)
Hypertension	1(Ref.)	1.21(0.93–1.57)	1.01(0.73–1.30)	1.35(0.98–1.86)	1.17(0.91–1.50)	1.37(1.02–1.68)	0.997
No hypertension	1(Ref.)	1.23(0.54–2.82)	1.07(0.36–3.14)	1.61(0.67–3.85)	2.18(1.18–4.06)	3.34(1.73–6.47)
Hypercholesterolemia	1(Ref.)	1.27(0.96–1.66)	1.08(0.81–1.45)	1.42(1.02–1.96)	1.36(1.04–1.74)	1.49(1.21–1.74)	0.291
No hypercholesterolemia	1(Ref.)	1.14(0.35–3.73)	0.66(0.28–1.57)	1.51(0.82–2.77)	1.27(0.70–2.25)	1.65(0.91–2.99)

Adjusted model was fully adjusted for age, gender, BMI, systolic blood pressure, smoking status, hypertension, dyslipidemia, hemoglobin A1c, estimated glomerular filtration rate, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, use of antidiabetic agents, antihypertensive medication and lipid-lowering medication. (When a variable is used as a research variable in the subgroup analysis, that variable will be excluded during adjustment.)

CTI C-reactive protein–triglyceride glucose index, BMI Body mass index