Table 3.

The correlations of the expressions of lncRNA-ANCR, EZH2 mRNA, EZH2 protein and H3K27me3 protein with pathological features of CRC patients

Feature	n	ANCR	EZH2 mRNA	EZH2 protein	H3K27me3 protein
Age
$⩽$ 60	80	0.24 $\pm$ 0.12	1.22 $\pm$ 0.42	1.38 $\pm$ 0.48	1.09 $\pm$ 0.33
$>$ 60	42	0.27 $\pm$ 0.13	1.29 $\pm$ 0.53	1.47 $\pm$ 0.59	1.13 $\pm$ 0.18
Lymphatic metastasis
No	63	0.21 $\pm$ 0.11	1.16 $\pm$ 0.45	1.32 $\pm$ 0.51	0.97 $\pm$ 0.19
Yes	59	0.28 $\pm$ 0.13${}^{\ast }$	1.33 $\pm$ 0.46${}^{\ast }$	1.51 $\pm$ 0.51${}^{\ast }$	1.22 $\pm$ 0.28${}^{\ast }$
Dukes stage
Stage A-B	56	0.20 $\pm$ 0.10	1.15 $\pm$ 0.48	1.31 $\pm$ 0.54	1.02 $\pm$ 0.13
Stage C-D	66	0.29 $\pm$ 0.13${}^{\ast }$	1.32 $\pm$ 0.43${}^{\ast }$	1.50 $\pm$ 0.49${}^{\ast }$	1.20 $\pm$ 0.37${}^{\ast }$
TNM stage
I–II	47	0.19 $\pm$ 0.11	1.09 $\pm$ 0.41	1.31 $\pm$ 0.59	0.95 $\pm$ 0.36
III–IV	75	0.28 $\pm$ 0.12${}^{\ast }$	1.34 $\pm$ 0.46${}^{\ast }$	1.48 $\pm$ 0.46${}^{\ast }$	1.24 $\pm$ 0.40${}^{\ast }$
Histological grade
Low-differentiated	83	0.24 $\pm$ 0.12	1.23 $\pm$ 0.42	1.39 $\pm$ 0.48	1.07 $\pm$ 0.31
Well-differentiated	39	0.27 $\pm$ 0.14	1.28 $\pm$ 0.54	1.46 $\pm$ 0.61	1.15 $\pm$ 0.09
Pathological types
Invasive type	12	0.31 $\pm$ 0.15	1.62 $\pm$ 0.51	1.90 $\pm$ 0.86	1.03 $\pm$ 0.19
Ulcerative type	76	0.23 $\pm$ 0.11	1.18 $\pm$ 0.36	1.33 $\pm$ 0.32	1.09 $\pm$ 0.38
Apophasis type	34	0.26 $\pm$ 0.14	1.24 $\pm$ 0.58	1.42 $\pm$ 0.86	1.14 $\pm$ 0.15

CRC, colorectal cancer; EZH2, enhancer of zeste homolog; TNM, tumor node metastasis; ${}^{\ast }$, 0.05 compared with the patients with no lymphatic metastasis/Duke A-B/TNM I–II.