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. 2026 Mar 12;14(3):637. doi: 10.3390/biomedicines14030637
MGB Microbiota–gut–brain
SCFAs Short-chain fatty acids
BDNF Brain-derived neurotrophic factor
GF Germ-Free
MDD Major depressive disorder
AHN Adult hippocampal neurogenesis
DG Dentate gyrus
HPA Hypothalamic–pituitary–adrenal
mPFC Medial prefrontal cortex
GABA Gamma-aminobutyric acid
fMRI Functional magnetic resonance imaging
5-HT Serotonin
DA Dopamine
NE Norepinephrine
ENS Enteric nervous system
MRIs Structural magnetic resonance imaging
DTI Diffusion tensor imaging
EEG Electroencephalogram
BBB Blood–brain barrier
ASD Autism spectrum disorders
ADHD Attention deficit hyperactivity disorder
EECs Enteroendocrine cells
PAMPs Pathogen-associated molecular patterns
CNS Central nervous system
NTS Nucleus of the solitary tract
DMV Dorsal motor nucleus of the vagus nerve
TNF Tumor necrosis factor
LPS Lipopolysaccharide
TLRs Toll-like receptors
IL-1β Interleukin-1 beta
IL-6 Interleukin-6
TNF-α Tumor Necrosis Factor-alpha
IFN-γ Interferon-gamma
PYY Peptide YY
GLP-1 Glucagon-like peptide-1
NPCs Neural progenitor cells
HDACs Histone deacetylases
LTP/LTD Long-term potentiation/Long-term depression
PSD-95 Postsynaptic density protein 95
NGF Nerve growth factor
GLIN Glial cell lineage-derived neurotrophic factor
JAK/STAT Janus Kinase/Signal Transducer and Activator of Transcription
NMDA N-Methyl-D-Aspartate
CUMS Chronic unpredictable mild stress
NMDAR2B N–methyl–D–aspartate Receptor 2B
NMDAR1 N–methyl–D–aspartate Receptor 1
NMDA2A N–methyl–D–aspartate Receptor 2A
mRNA messenger RNA
GAD Glutamate decarboxylase
5-HT1A 5-Hydroxytryptamine 1A receptor
DRD1 Dopamine receptor D1
ADRA-2A Alpha-2A adrenergic receptor
NR3C2 Mineralocorticoid receptor
CNR1 Cannabinoid receptor type 1
Adrb3 β3-adrenergic receptor
Avpr1a Vasopressin 1a receptor
Drd5 Dopamine Receptor D5
Htr2b 5-hydroxytryptamine receptor 2B
SERT 5-HT transporter
SSRIs Selective serotonin reuptake inhibitors
THP-1 Human monocytic leukemia cell line
IBS Irritable bowel syndrome
miRNAs microRNAs
NPY Neuropeptide Y
RCTs Randomized controlled trials
CSF Cerebrospinal fluid
n-3 PUFA Omega-3 polyunsaturated fatty acids
EPA Eicosapentaenoic acid
DHA Docosahexaenoic acid
VEGF-A Vascular endothelial growth factor-A
DCX Doublecortin
GABAA/B Gamma-aminobutyric acid receptor types A and B
PI3K/Akt Phosphoinositide 3-kinase/protein kinase B
RCT Randomized controlled trial
OB Oral probiotic
iPSC Induced pluripotent stem cells
FMT Fecal microbiota transplantation