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. 2026 Mar 16;15(6):523. doi: 10.3390/cells15060523
cGAS cyclic GMP-AMP synthase
STING stimulator of interferon genes
SASP senescence-associated secretory phenotype
D-gal D-galactose
Cxcl-10 C-X-C motif chemokine ligand 10
Il-1β interleukin 1 beta
TBK1 TANK binding kinase 1
AD Alzheimer’s disease
PD Parkinson’s disease
P16 cyclin-dependent kinase inhibitor 2A
P21 cyclin-dependent kinase inhibitor 1A
2′, 3′-cGAMP 2′, 3′-cyclic GMP-AMP
CMC-Na sodium carboxymethylcellulose
PBS phosphate-buffered saline
pTBK1 phosphorylated TBK1
IBA1 induction of brown adipocytes 1
P2ry12 purinergic receptor P2Y, G-protein coupled 12
TUBB3 Tubulin beta 3
CD68 cluster of differentiation 68
DAPI 4′,6-diamidino-2-phenylindole
GM130 golgi autoantigen
SA-β-gal senescence-associated β-galactosidase
SDS-PAGE sodium dodecyl sulfate polyacrylamide gel electrophoresis
pSTING phosphorylated STING
GAPDH glyceraldehyde-3-phosphate dehydrogenase
FBS fetal bovine serum
dsDNA double-stranded DNA
DMSO dimethyl sulfoxide
ELISA enzyme-linked immunosorbent assay
TNF-α tumor necrosis factor alpha
cDNA complementary DNA
RT-qPCR real-time quantitative PCR
DEGs differentially expressed genes
GO gene ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
SEM standard error of the mean
CA1 cornu ammonis 1
DG dentate gyrus
8-OHdG 8-hydroxy-2′-deoxyguanosine
CA3 cornu ammonis 3
EC entorhinal cortex
Ccl-2 C-C motif chemokine ligand 2
Ifi-44 interferon-induced protein 44
Il-18 interleukin 18
GSEA gene set enrichment analysis
ER endoplasmic reticulum
CNS central nervous system
NAD nicotinamide adenine dinucleotide