| cGAS | cyclic GMP-AMP synthase |
| STING | stimulator of interferon genes |
| SASP | senescence-associated secretory phenotype |
| D-gal | D-galactose |
| Cxcl-10 | C-X-C motif chemokine ligand 10 |
| Il-1β | interleukin 1 beta |
| TBK1 | TANK binding kinase 1 |
| AD | Alzheimer’s disease |
| PD | Parkinson’s disease |
| P16 | cyclin-dependent kinase inhibitor 2A |
| P21 | cyclin-dependent kinase inhibitor 1A |
| 2′, 3′-cGAMP | 2′, 3′-cyclic GMP-AMP |
| CMC-Na | sodium carboxymethylcellulose |
| PBS | phosphate-buffered saline |
| pTBK1 | phosphorylated TBK1 |
| IBA1 | induction of brown adipocytes 1 |
| P2ry12 | purinergic receptor P2Y, G-protein coupled 12 |
| TUBB3 | Tubulin beta 3 |
| CD68 | cluster of differentiation 68 |
| DAPI | 4′,6-diamidino-2-phenylindole |
| GM130 | golgi autoantigen |
| SA-β-gal | senescence-associated β-galactosidase |
| SDS-PAGE | sodium dodecyl sulfate polyacrylamide gel electrophoresis |
| pSTING | phosphorylated STING |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| FBS | fetal bovine serum |
| dsDNA | double-stranded DNA |
| DMSO | dimethyl sulfoxide |
| ELISA | enzyme-linked immunosorbent assay |
| TNF-α | tumor necrosis factor alpha |
| cDNA | complementary DNA |
| RT-qPCR | real-time quantitative PCR |
| DEGs | differentially expressed genes |
| GO | gene ontology |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| SEM | standard error of the mean |
| CA1 | cornu ammonis 1 |
| DG | dentate gyrus |
| 8-OHdG | 8-hydroxy-2′-deoxyguanosine |
| CA3 | cornu ammonis 3 |
| EC | entorhinal cortex |
| Ccl-2 | C-C motif chemokine ligand 2 |
| Ifi-44 | interferon-induced protein 44 |
| Il-18 | interleukin 18 |
| GSEA | gene set enrichment analysis |
| ER | endoplasmic reticulum |
| CNS | central nervous system |
| NAD | nicotinamide adenine dinucleotide |