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. 2026 Mar 17;15(6):535. doi: 10.3390/cells15060535
GC Gastric cancer
TME Tumor microenvironment
ST Spatial transcriptomics
NGS Next-Generation Sequencing
FFPE Formalin-fixed paraffin-embedded
DBiT-seq Deterministic Barcoding in Tissue for spatial omics sequencing
ISH In situ hybridization
IMC Imaging Mass Cytometry
MIBI-TOF Multiplexed Ion Beam Imaging
DSP Digital Spatial Profiling
ROI Region of Interest
CNV Copy number variation
MSI Mass spectrometry imaging
MALDI-MSI Matrix-assisted laser desorption/ionization mass spectrometry imaging
DESI-MSI Desorption electrospray ionization–mass spectrometry imaging
SIMS Secondary ion mass spectrometry
TCGA The Cancer Genome Atlas
ACRG Asian Cancer Research Group
EBV Epstein–Barr virus
MSI Microsatellite Instability
CIN Chromosomal Instability
GS Genomically Stable
ITH Intra-tumoral heterogeneity
MSC Metabolic signature cluster
MP Meta-program
PCC Poorly cohesive carcinoma
CSC Cancer stem cell
CAF Cancer-associated fibroblast
DGC Diffuse Gastric Cancer
SRC Signet ring cell
PDC Poorly differentiated cell
GSRC Gastric signet ring cell carcinoma
ICI Immune checkpoint inhibitor
CPS Combined positive score
TMB-H High tumor mutational burden
PMN-MDSC Polymorphonuclear myeloid-derived suppressor cell
CTL Cytotoxic T lymphocyte
ICEP Immune checkpoint expression pattern
ERAD Endoplasmic reticulum-associated degradation
T-DXd Trastuzumab deruxtecan
PMC_P Precancerous metastatic niche
GCPM Gastric cancer peritoneal metastasis
THSD4 Thrombospondin type 1 domain-containing protein 4
INT/S Intestinal with stem-like features
TLS Tertiary lymphoid structure
iTLS Intra-tumoral tertiary lymphoid structure
pTLS Peritumoral tertiary lymphoid structure
HEV High endothelial venule
GCY Young gastric cancer
TCR Tumor core region
CAT Cancer-adjacent tissues
SARIFA Stroma AReactive Invasion Front Areas