FIGURE 2.

Simulated time series of the concentrations of cytosolic NADPH, oxygen, and NADP^· radical as well as superoxide and hydrogen peroxide in the phagosome. The simulations were made using the model listed in Table 1 and Table 2. The flux of formation of NADPH (k₁₂) was set at 30 μM/s. Other parameters as listed in Table 1. The initial concentrations of ferric peroxidase and melatonin were both 300 μM. The initial concentration of all other substances was zero.