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. 2003 Jan;84(1):154–170. doi: 10.1016/S0006-3495(03)74839-5

TABLE 2.

Two-substrate case

Regime Macroscopic steady state of x Sensitivity amplification (≈Fano factor) Relaxation rate constant
kx < ky Inline graphic Inline graphic Inline graphic
kx = ky Inline graphic Inline graphic Inline graphic
kx > ky Inline graphic Inline graphic Inline graphic

Assuming Kx = Ky and kX < vmax. In this regime, the deviation between the macroscopic steady state and the average value is significant.

Approximation when product inhibition dominates over dilution.