FIGURE 6.
An experimental discrimination between two models for insertion of RG-C14:0 into POPC/cholesterol (6/4; liquid-ordered phase) bilayer membranes. The experimental trace was fitted to two models: 1) a model (Model III, Appendix) in which insertion into the membrane occurs via diffusional contact between the membrane and an aqueous phase FLA monomer and 2) a model (Model IV, Appendix) in which insertion into the membrane occurs via diffusional contact between the membrane and a protein–FLA complex. The lower panels in this figure show the residuals for the first fit (A) and for the second fit (B).