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. 2026 Mar 13;27(6):2628. doi: 10.3390/ijms27062628
ATF6 Activating Transcription Factor 6
bHLH-ZIP basic helix-loop-helix leucine zipper
CDS Coding sequence
DEGs Differentially Expressed Genes
Dsc Defective for SREBP cleavage
DTT dithiothreitol
ER Endoplasmic Reticulum
ERAD Endoplasmic Reticulum-Associated Degradation
GO Gene Ontology
INSIG Insulin induced gene
IRE1 Inositol-Requiring Enzyme 1
MAFFT Multiple Alignment using Fast Fourier Transform
MVA Mevalonate
NES Normalized Enrichment Score
ORF Open Reading Frame
padj Adjusted p-value
PERK PKR-like ER kinase
RNA-seq RNA sequencing
RPKM Reads Per Kilobase per Million mapped reads
S1P Site-1 Protease
S2P Site-2 Protease
SCAP SREBP Cleavage-Activating Protein
SPP Signal peptide peptidase
SPPL Signal peptide peptidase like
SRE Sterol Regulatory Element
SREBP Sterol Regulatory Element-Binding Protein
TM Transmembrane
TMHMM TransMembrane Hidden Markov Model
TPM Transcripts Per Million
UPR Unfolded Protein Response
XBP1 X-box Binding Protein 1
XBP1s Spliced XBP1
XBP1u Unspliced XBP1