The Hill coefficient at half activation, NH50, is plotted as a function of γ and Q at three levels of μ. The parameter γ is varied between 5 and 45 in increments of 2.5, whereas the parameter Q is varied between 1.25 and 3 in increments of 0.25. The contour lines show the isoclines for levels as labeled and increase with an increment of 2. Results for μ = 5 (A), 10 (B), and 15 (C). In general, NH50 is an increasing function of γ, μ, and Q. However, for the μ = 5 case, the dependence on Q is nonmonotonic, a feature investigated further in Fig. 6 (see text for details).