EVs	Extracellular Vesicles
LE-EVs	Lung Epithelial-derived Extracellular Vesicles
CS	Cigarette Smoke
CSE	Cigarette Smoke Extract
ECA	Electronic Cigarette Aerosol
ECVC	Electronic Cigarette Vapour Condensate
HTP	Heated Tobacco products
ENDS	Electronic Nicotine Delivery Systems
PG	Propylene Glycol
VG	Vegetable Glycerine
COPD	Chronic Obstructive Pulmonary Disease
AJ	Adheren Junction
TJ	Tight Junction
MSCs	Mesenchymal Stem Cells
DEEPs	Differentials Expressed Exosomal Proteins
HBE	Human Bronchial Epithelial
FACS	Fluorescent-Activated Cell Sorting
TEM	Transmission Electron Microscopy
SEM	Scanning Electron Microscopy
RTq-PCR	Reverse Transcription-quantitative Polymerase Chain Reaction
UC	Ultracentifucation
SEC	Size Exclusion Chromatography
iTRAQ	Isobaric Tag for Relative and Absolute Quantitation