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. 2026 Mar 12;27(6):2617. doi: 10.3390/ijms27062617
Abbreviation Definition
α-MSH Alpha-melanocyte-stimulating hormone
AKT Protein kinase B
ATM Ataxia telangiectasia mutated
ATR Ataxia telangiectasia and Rad3-related
bFGF Basic fibroblast growth factor
CDK1 Cyclin-dependent kinase 1
cAMP Cyclic adenosine monophosphate
CHK1 Checkpoint kinase 1
CHK2 Checkpoint kinase 2
CPD Cyclobutane pyrimidine dimer
DDR DNA damage response
DMEM Dulbecco’s modified Eagle’s medium
DPBS Dulbecco’s phosphate-buffered saline
EB Embryoid body
EGF Epidermal growth factor
FACS Fluorescence-activated cell sorting
FBS Fetal bovine serum
GADD45α Growth arrest and DNA damage-inducible protein alpha
GFP Green fluorescent protein
GUSB Beta-glucuronidase
γH2AX Phosphorylated histone H2AX
HRP Horseradish peroxidase
iPSC Induced pluripotent stem cell
IRDS Interferon-related DNA damage resistance signature
MAPK Mitogen-activated protein kinase
MC1R Melanocortin 1 receptor
MITF Microphthalmia-associated transcription factor
MX2 Myxovirus resistance protein 2
NAMs New Approach Methodologies
nbUVB Narrowband ultraviolet B
NER Nucleotide excision repair
NHM Normal human melanocytes
OSKM OCT4, SOX2, KLF4, and c-MYC
PARP Poly(ADP-ribose) polymerase
PBS Phosphate-buffered saline
PKA Protein kinase A
PMA Phorbol 12-myristate 13-acetate
PMEL Premelanosome protein
QC Quality control
ROS Reactive oxygen species
RPPA Reverse phase protein array
RT-qPCR Quantitative reverse-transcription polymerase chain reaction
SCF Stem cell factor
SSEA-4 Stage-specific embryonic antigen 4
STAT1 Signal transducer and activator of transcription 1
TG Test guideline
TYR Tyrosinase
UV Ultraviolet
XAF1 XIAP-associated factor 1