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Fast calcium release at six-channel release site in conditions specified by Scenario I. The current through both Ca2+ and K+ channel in the central element on the ER membrane are shown in the upper panels (ICa and IK, respectively). Other notations as in Fig. 7. Over the simulated 250-ms period after IP3 stimulation, calcium is released through the IP3Rs cluster during the first 26 ms only. The stationary buffer level is 120 μM.
