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Summary of the results obtained by Ala scan on the octapeptide NFGAILSS
| Aggregated structures | Polymerization kinetics | |
|---|---|---|
| AFGAILSS | Short and branched fibers | Faster aggregation |
| NAGAILSS | Nonfibril organization | |
| NFAAILSS | Long fibers | Similar velocity |
| NFGAALSS | Long fibers | Slower kinetics |
| NFGAIASS | Long fibers | Slower kinetics |
The results are compared with the wild-type derivative. The Ala substitution is shown in bold.
