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Effects of Sap C and synthetic peptides on DSPC/POPS phospholipid membranes
| DSPC/POPS molar ratio
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Patch formation
|
Membrane destabilization
|
|||||||
| (10:0) | (10:1) | (10:2.5) | (10:5) | (10:0) | (10:1) | (10:2.5) | (10:5) | |
| Sap C | +* | + | + | + | − | − | + | + |
| H1 peptide | − | − | − | − | − | − | − | − |
| H1/Sap C† | +* | + | + | + | − | − | + | + |
| H2 peptide | + | + | + | + | − | − | − | − |
| H2/Sap C† | + | + | + | + | − | − | − | − |
| H1/H2† | ND‡ | ND‡ | +* | + | ND‡ | ND‡ | + | + |
Partial formation with a surface coverage <20%.
Sequential addition.
Not determined.
