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. 2026 Feb 25;16(3):374. doi: 10.3390/life16030374
CNS central nervous system
GBM  glioblastoma
LGG  low-grade glioma
IHC  immunohistochemical
GI  genomic instability
MIN, MSI  microsatellite instability
CIN  chromosomal instability
WHO  World Health Organization
IDH  isocitrate dehydrogenase
ODG  oligodendroglioma
HGG  high-grade glioma
CAG  circumscribed astrocytic glioma
PCA  pilocytic astrocytoma
HGAP  high-grade astrocytoma with piloid features
PXA  pleomorphic xanthoastrocytoma
MN1  MN1 proto-oncogene, transcriptional regulator
DNA  deoxyribonucleic acid
CTx  chemotherapy
RT  radiotherapy
SNI single nucleotide instability
MMR  mismatch repair
AP-PCR  arbitrarily primed polymerase chain reaction
5-HTR  5-hydroxytryptamine (serotonine) receptor
AC  adenylyl cyclase
ATP  adenosine triphosphate
cAMP  3′-5′-cyclic adenosine monophosphate
PKA  protein kinase A
EPAC exchange protein activated by cAMP
CREB CRE-binding protein
CREM cAMP-responsive modulator
ATF1  activating transcription factor 1
Rap1 Ras-associated protein 1
Rap2 Ras-associated protein 2
5-HTR4  5-hydroxytryptamine (serotonine) receptor 4
TSG  tumor-suppressor gene
PDE  phosphodiesterase
PDE4D  cAMP-specific 3′,5′-cyclic phosphodiesterase 4D
CA12 F  carbonic anhydrase 12 forward
CA 9 R  carbonic anhydrase 9 reverse
MDR2  multi-drug resistance 2
C-MYC1 cellular myelocytomatosis oncogene 1
MgCl2 magnesium chloride
dNTP  deoxyribonucleoside triphosphate
NTC  no-template control
FEPE  formalin-fixed paraffin-embedded
DAB  diaminobenzidine 
IRS  immunoreactive score
SI  staining intensity
PP  percentage of positive cells
OR  odds ratio