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. 2003 May;84(5):2852–2870. doi: 10.1016/S0006-3495(03)70014-9

FIGURE 2.

FIGURE 2

Deterministic simulation of first phase transient and oscillations after addition of glucose (Eqs. 1–6, Methods). (A–C) A medium cell, representing a medium islet. Parameters are as in Modeling section, except gKATP, which is initially 1 nS and stepped down to 55 pS at T = 50 s to simulate the addition of glucose. For simplicity, no attempt is made to model the latency period or the phase 0 decrease of calcium. (D–F) A slow cell, representing a slow islet. Parameters as in A–C, except gKATP is stepped to 62 pS.