FIG. 1.

Suppression of DTH responses to a heterologous antigen by ABF. BALB/c mice were sensitized with OVA alone or in combination with various amounts of ABF (in micrograms, as indicated) or 100 μg of rABA-1. Challenge occurred 7 days later with HAO, and the DTH responses were assessed over the subsequent 24 h. The members of the unimmunized control group (group 0) were challenged with HAO. The DTH responses are expressed as the mean + standard error of the mean increase in footpad thickness for five mice per group. An asterisk indicates that there was a significant difference compared to the value for the OVA-sensitized group (P ≤ 0.001).