FIG. 7.
Titration of phage 153A-5 in V. vulnificus MO6-24/0-infected mice. Iron-dextran-treated mice were inoculated s.c. with 1,150 CFU of V. vulnificus MO6-24/0. Mice were injected i.v. with BSG (control) (−) or with 108 PFU (8), 106 PFU (6), or 104 PFU (4) of phage 153A-5 immediately after s.c. infection. Samples were harvested 14 to 20 h later. Data are means and standard deviations for log CFU per gram of skin lesion (Lesion CFU), log CFU per gram of liver lesion (Liver CFU), and rectal temperature (Temp). For lesion score (Lesion), the mean is shown. Single asterisks indicated that values for the phage-treated group were significantly different from those for the control group (2.5 × 10−5 < P < 0.02). Double asterisks indicate that values for the 108 PFU-treated group were significantly different from those for the 106 or 104 PFU-treated group (P < 0.02).