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. 2026 Mar 1;19(3):408. doi: 10.3390/ph19030408
ACC Acetyl-CoA Carboxylase
ACTF4 Activating Transcription Factor 4
ALT Alanine Aminotransferase
AML12 Alpha Mouse Liver 12 Cell Line
AMPK AMP-Activated Protein Kinase
AST Aspartate Aminotransferase
AWARD Assessment of Weekly Administration of LY2189265 (Dulaglutide) in Diabetes
β-cells Pancreatic Beta Cells
BMI Body Mass Index
cAMP Cyclic Adenosine Monophosphate
CHOP C/EBP Homologous Protein
CREB cAMP Response Element-Binding Protein
CVD Cardiovascular Disease
DGAT1/2 Diacylglycerol Acyltransferase 1/2
D-LIFT Dulaglutide Effect on Liver Fat in Type 2 Diabetes
DPP-4 Dipeptidyl Peptidase-4
EA Elaidic Acid
ER Endoplasmic Reticulum
Ex-ER Exenatide Extended-Release
FFA Free Fatty Acid
FDA Food and Drug Administration
FOXA1 Forkhead Box A1
FOXO1 Forkhead Box O1
FAS Fatty Acid Synthase
G6Pase Glucose-6-Phosphatase
GGT Gamma-Glutamyl Transferase
GIP Glucose-Dependent Insulinotropic Polypeptide
GLP-1 Glucagon-Like Peptide-1
GLP-1R Glucagon-Like Peptide-1 Receptor
GLP-1RA Glucagon-Like Peptide-1 Receptor Agonist
GRP78 Glucose-Regulated Protein 78
HCC Hepatocellular Carcinoma
HepG2 Human Hepatocellular Carcinoma Cell Line
HFC Hepatic Fat Content
HNF4α Hepatocyte Nuclear Factor 4 Alpha
HO-1 Heme Oxygenase-1
HOMA-IR Homeostasis Model Assessment of Insulin Resistance
Huh7 Human Hepatoma Cell Line
IgG4 Immunoglobulin G4
IR Insulin Resistance
IRS Insulin Receptor Substrate
JS-1 Hepatic Stellate Cell Line
L02 Normal Human Liver Cell Line
LPS Lipopolysaccharide
MASLD Metabolic Dysfunction–Associated Steatotic Liver Disease
MASH Metabolic Dysfunction–Associated Steatohepatitis
MET Metformin
MRI-PDFF Magnetic Resonance Imaging–Proton Density Fat Fraction
MS Metabolic Syndrome
NQO1 NADH Quinone Dehydrogenase 1
Nrf2 Nuclear Factor Erythroid 2–Related Factor 2
OA Oleic Acid
PA Palmitic Acid
PEPCK Phosphoenolpyruvate Carboxykinase
PHHs Primary Human Hepatocytes
PKA Protein Kinase A
PPARα/PPARγ Peroxisome Proliferator-Activated Receptor Alpha/Gamma
QW Once Weekly
QD Once Daily
RCT Randomized Controlled Trial
ROS Reactive Oxygen Species
SCD1 Stearoyl-CoA Desaturase-1
SHP Small Heterodimer Partner
SREBP-1c Sterol Regulatory Element-Binding Protein-1c
T2D Type 2 Diabetes
TCF4 T-Cell Factor 4