Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hypothetical five-state models of rSGLT1 in the absence of glucose. In both models, transitions C2⇔C3 and C3⇔C4 correspond to conformational changes of the unloaded carrier. (A) C1⇔C2 is a single or double Na+ binding/debinding event, and C0⇔C1 is a conformational change in the protein which exposes the sugar-binding domain to glucose. (B) Both C0⇔C1 and C1⇔C2 are single Na+ binding/debinding events.
