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Levels of IL-1β (A), TNF-α (B), and IL-10 (C) in lung tissue homogenate recovered before and at 2, 5, and 12 days after thesingle infection or the last infection of the multiple-infection rats. Cytokine levels were measured by ELISA as described in Materials and Methods. Each data point represents the means ± standard errors of the means of five rats. An asterisk indicates a P value of <0.05 compared to that of uninfected controls.
