AHR after single (A) or multiple (B) S. venezuelensis infection in rats. The change in intratracheal pressure in response to acetylcholine was used as a measurement of AHR in control and S. venezuelensis-infected rats (at 2, 5, 7, and 12 days after the last infection). Each data point represents the means ± standard errors of the means of 10 to 12 rats from three experiments. The values obtained at 5 days postinfection (A) and at 2, 5, and 7 days after reinfection (B) were statistically different (P ≤ 0.05) from values obtained from uninfected rats.