TABLE 2.
Cyclic peptide thermodynamic parameters of folding
| Tm (°C) | ΔT(°C) | ΔHf (kJ/mol) | ΔSf (J/mol·K) | |
|---|---|---|---|---|
| 6-mer* | 37 | 387 | −10 | −31 |
| 10-mer | 50.5 ± 0.3† | 139.4 ± 12.4 | −29.1 ± 0.4 | −89.8 ± 1.4 |
| 14-mer | 71.0 ± 2.3 | 84.1 ± 5.0 | −48.3 ± 0.5 | −140.4 ± 1.8 |
The breadth of the transition in this case precludes a unique fit; included for comparative purposes only.
Standard deviations are reported. Thermodynamic parameters are derived from a two-state model and a van't Hoff analysis.