Mean information content for Hamilton square walks as a function of sequence separation for single distance constraints (N = 9, 16, 25, 49), a full enumeration ensemble (FE) (N = 16) and a stochastic, nonexhaustive ensemble of unconstrained conformations (FES) (N = 49). ○: 16-mer FE unit; □: 49-mer FES; ⋄: 9-mer HW; ▵: 16-mer HW; ◃: 25-mer HW; ▹: 49-mer HW.