TABLE 2.

Estimates of secondary structure in PrP (113–120) from analysis of CD spectra

	% of secondary structure for PrP (113–120)
	α-helix	β-sheet	β-turn	Random coil
a. % TFE
0	3.2	6.2	23.7	59.6
5	3.5	12.6	24.0	58.1
10	9.3	13.1	26.3	51.7
15	7.7	16.4	24.5	52.4
20	9.6	18.7	23.1	47.9
25	11.9	18.6	24.8	47.9
30	12.4	17.6	25.4	46.3
40	17.5	17.4	24.5	43.2
50	20.7	16.3	21.8	40.9
60	22.0	21.4	19.0	36.9
70	25.9	21.7	19.8	34.9
80	24.7	24.3	19.2	30.7
90	28.4	17.7	20.4	34.0
95	26.8	20.7	21.1	32.0
100	28.5	20.9	21.0	29.6
b. 5% SDS solution	24.3	13.0	16.1	42.9