TABLE 1.
Gene expression profiling of TNF-α-stimulated Hc cells with microarraya
| Accession no. | Ratio | Description | Abbreviation |
|---|---|---|---|
| Y00787 | 14.10 | IL-8 precursor | IL-8 |
| AF003521 | 10.02 | jagged2 | JAG2 |
| M57730; M37476 | 5.03 | eph-related receptor tyrosine kinase ligand 1 precursor | EPGL1 |
| M90813; D13639 | 4.84 | Cyclin D2 | CCND2 |
| M92357 | 3.20 | B94 protein | |
| X14420 | 3.03 | Procollagen 3 alpha 1 subunit precursor | COL3A1 |
| AF039067; AF071596 | 2.63 | IEX-1L anti-death protein | |
| L20814 | 2.61 | Glutamate receptor 2 precursor | GLUR-2 |
| Y00285; J03528 | 2.41 | IGF2R | IGF2R |
| AF010127; Y14039; Y14040 | 2.40 | FLICE-like inhibitory protein | FLIP |
| M95667; M11730 | 2.34 | erbB2 proto-oncogene | |
| U02081 | 2.14 | Rho guanine nucleotide regulatory protein, alternate splice form | NET1 |
| M73812 | 2.14 | Cyclin E | CCNE |
| U14417 | 2.13 | RalGDSB | RALGEF |
| U69108 | 2.09 | TRAF5 | |
| AF011466 | 2.08 | G protein-coupled receptor EDG4 | |
| X75042 | 2.08 | c-rel proto-oncogene | |
| D49742; S83182 | 2.04 | HGF-like protein | |
| U58334 | 2.03 | Bcl2 and p53 binding protein | BBP/53BP2 |
a
Hc cells were treated with or without TNF-α for 1 h. mRNA was isolated, reverse-transcribed into fluorescent-labeled cDNA, and hybridized to glass microarray containing 1,081 genes. The data show 19 genes which are increased by two times above in expression ratios (post-TNF/no TNF).