Table 2.
Inflammatory bowel disease characteristics.
| Control (N = = 200) | Case (N = = 87) | P-value | |
|---|---|---|---|
| Subtype | .481 | ||
| CD | 89 (44.5%) | 32 (36.8%) | |
| UC | 105 (52.5%) | 52 (59.8%) | |
| IC | 6 (3.0%) | 3 (3.4%) | |
| Maximal endoscopic extent of CD in past | .861 | ||
| Ileal | 20 (22.5%) | 7 (21.9%) | |
| Ileocolonic | 56 (62.9%) | 19 (59.4%) | |
| Colonic | 13 (14.6%) | 6 (18.8%) | |
| Maximal endoscopic extent of UC in past | .0321 | ||
| Proctitis | 10 (9.5%) | 1 (1.9%) | |
| Left-sided | 19 (18.1%) | 4 (7.7%) | |
| Extensive | 74 (70.5%) | 46 (88.5%) | |
| Maximal endoscopic extent of IC in past | |||
| Ileocolonic | 3 (1.5%) | 2 (2.3%) | .631 |
| Colonic | 3 (1.5%) | 1 (1.1%) | .821 |
| Perianal disease presentb | 25 (28.1%) | 16 (50.0%) | .0251 |
| Backwash ileitis present | 8 (7.6%) | 15 (28.8%) | <.001a |
| PSC present | 15 (7.5%) | 25 (28.7%) | <.001a |
| History of cholangiocarcinoma | 3 (1.5%) | 6 (6.9%) | .021 |
| Prior liver transplant | 5 (2.5%) | 11 (12.6%) | <.001a |
| Family history of colorectal cancer | 24 (12.0%) | 12 (13.8%) | .891 |
| Current/former tobacco use | 57 (28.5%) | 24 (27.6%) | .871 |
| Previous surgery (prior to 1/1/2007) | .251 | ||
| Ileocecal resection | 14 (56.0%) | 2 (25.0%) | |
| Colon segment resection | 2 (8.0%) | 2 (25.0%) | |
| Hemicolectomy | 2 (8.0%) | 2 (25.0%) | |
| Other | 7 (28.0%) | 2 (25.0%) |
Abbreviations: CD, Crohn’s disease; IC, indeterminate colitis; PSC, primary sclerosing cholangitis; UC, ulcerative colitis.
aPearson’s Chi-squared test.
bPatients with UC and IC were not included.