Table 4.
Cox model for effect of nonconventional versus conventional lesions in the pre (prior to 2015) versus post (2015 to present) high-definition endoscopic era.
| Effect | Location level | |
|---|---|---|
| HR (95% CI) | P-value | |
| Cumulative conventional lesion count (pre-HD)a | 1.79 (0.84, 3.81) | .13 |
| Cumulative conventional lesion count (post-HD)a | 2.79 (1.62, 4.77) | <.001 |
| Cumulative nonconventional lesion count (pre-HD)a | 2.39 (1.60, 3.57) | <.001 |
| Cumulative nonconventional lesion count (post-HD)a | 1.62 (0.86, 3.06) | .13 |
| Age (per 5 years) | 1.12 (1.01, 1.24) | .03 |
| Female | 0.85 (0.43, 1.67) | .64 |
| Year of first surveillance endoscopic procedure | 1.14 (1.02, 1.27) | .03 |
| Surveillance endoscopic procedure prior to 2007 | 0.72 (0.31, 1.68) | .45 |
| IBD duration, years | 1.00 (0.98, 1.02) | .96 |
| PSC | 3.63 (1.24, 10.64) | .02 |
| Cholangiocarcinoma | 1.65 (0.29, 9.41) | .57 |
| Liver transplant | 1.06 (0.23, 4.96) | .94 |
| History of invisible low-/high-grade dysplasia | 36.4 (16.1, 82.3) | <.001 |
| History of other invisible dysplasia | 2.06 (0.87, 4.86) | .10 |
Abbreviations: CI, confidence interval; HR, hazard ratio; IBD, inflammatory bowel disease; PSC, primary sclerosing cholangitis.
aSquare-root transformation was used.