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. 2003 Aug;85(2):982–995. doi: 10.1016/S0006-3495(03)74537-8

FIGURE 4.

FIGURE 4

Peptide-to-lipid titration experiments of penetratin into mixed DOPC/DOPG LUV of different molar fraction of DOPG, XPG (see figure). Aliquots (δVsyr) of penetratin solution (Psyr) were titrated into a lipid dispersion. The left panel shows the calorimeter tracings. The right panel shows the differential heat of reaction as a function of the molar ratio peptide-to-lipid, (P/L), in the sample cell. The experimental conditions are Psyr = 0.2 mM, L0 = 0.4 mM, δVsyr = 10 μl (XPG = 0, 0.25, 0.5); Psyr = 0.4 mM, L0 = 0.2 mM, δVsyr = 7 μl (XPG = 0.75), and Psyr = 0.4 mM, L0 = 0.17 mM, δVsyr = 10 μl (XPG = 1.0). The ranges I–IV indicated by dotted lines are defined in Fig. 9. See text.