Table 2.
Mean and standard deviation for the Digit Symbol Substitution Test (DSST) and Modified Mini-Mental Status Examination (3MS) across time points across sexes and APOE genotypes
| Test | Sex | Year | APOE ε2 | APOE ε3 | APOE ε4 |
|---|---|---|---|---|---|
| DSST | Female | 1 | 37.1 (14.4) | 37.7 (14.3) | 35.5 (15.6) |
| 5 | 35.5 (13.5) | 35.0 (13.9) | 31.9 (14.8) | ||
| 8 | 33.3 (13.6) | 33.2 (14.2) | 29.7 (14.5) | ||
| 10 | 32.5 (13.6) | 32.2 (13.8) | 28.3 (14.6) | ||
| Male | 1 | 31.8 (15.1) | 35.1 (14.0) | 32.0 (15.0) | |
| 5 | 30.0 (14.5) | 32.8 (13.9) | 29.0 (14.8) | ||
| 8 | 28.5 (14.4) | 30.4 (13.6) | 26.2 (14.5) | ||
| 10 | 27.1 (13.6) | 29.4 (13.4) | 25.4 (14.1) | ||
| 3MS | Female | 1 | 90.7 (7.7) | 91.2 (7.3) | 89.2 (9.8) |
| 3 | 90.2 (8.2) | 90.5 (7.9) | 87.5 (10.9) | ||
| 5 | 90.0 (8.8) | 90.0 (8.6) | 86.9 (12.0) | ||
| 8 | 88.5 (9.2) | 87.6 (10.1) | 84.3 (12.8) | ||
| 10 | 87.9 (10.2) | 86.8 (11.0) | 83.0 (14.0) | ||
| Male | 1 | 89.2 (9.6) | 90.3 (7.9) | 87.6 (9.5) | |
| 3 | 88.6 (9.8) | 89.8 (8.6) | 86.1 (11.1) | ||
| 5 | 88.7 (9.9) | 90.2 (8.5) | 86.6 (10.5) | ||
| 8 | 86.4 (11.4) | 87.3 (9.8) | 82.4 (13.3) | ||
| 10 | 86.1 (11.3) | 87.0 (10.3) | 81.4 (13.9) |