Table 3.
Full outputs for the linear models stratified by sex examining APOE genotype differences in cognitive outcomes
| DSST Initial | DSST Slope | 3MS Initial | 3MS Slope | |
|---|---|---|---|---|
| Female | ||||
| APOE ε3 (Reference) | ||||
| APOE ε2 | β = 1.14; p = 0.117 | β = 0.04; p = 0.230 | β = 0.38; p = 0.381 | β = 0.15; p = 0.002 |
| APOE ε4 | β=-0.50; p = 0.366 | β=-0.10; p = < 0.001 | β=-0.98; p = 0.003 | β=-0.13; p = < 0.001 |
| Male | ||||
| APOE ε3 (Reference) | ||||
| APOE ε2 | β=-0.32; p = 0.645 | β = 0.04; p = 0.152 | β = 0.21; p = 0.615 | β = 0.06; p = 0.215 |
| APOE ε4 | β=-1.13; p = 0.045 | β=-0.07; p = 0.005 | β=-1.66; p = < 0.001 | β=-0.22; p = < 0.001 |
| Race (Reference: Black) | β = 9.03; p = < 0.001 | β=-0.00; p = 0.776 | β = 4.54; p = < 0.001 | β = 0.22; p = < 0.001 |
| Site (Reference: Memphis) | β = 3.38; p = < 0.001 | β = 0.02; p = 0.105 | β = 1.43; p = < 0.001 | β = 0.29; p = < 0.001 |
| Age | β=-0.83; p = < 0.001 | β=-0.01; p = < 0.001 | β=-0.32; p = < 0.001 | β=-0.04; p = < 0.001 |
| Education | ||||
| Completed High School (Reference) | ||||
| Did not Complete High School | β=-7.68; p = < 0.001 | β = 0.01; p = 0.543 | β=-4.20; p = < 0.001 | β=-0.16; p = < 0.001 |
| Greater than High School | β = 4.46; p = < 0.001 | β = 0.02; p = 0.176 | β = 2.56; p = < 0.001 | β = 0.14; p = < 0.001 |
| Health Score Composite | β=-1.55; p = < 0.001 | β=-0.02; p = 0.007 | β=-0.35; p = 0.005 | β=-0.03; p = 0.011 |
Significant associations are presented in boldface. Digit Symbol Substitution Test (DSST), Modified Mini-Mental Status Examination (3MS), and Body Mass Index (BMI)