Table 4.
Comparison of ASyS clinical manifestations between our cohort and European cohorts
| Variable | Our cohort | Hum et al. [19] |
|---|---|---|
| Number of cases | 48 | 649 |
| Female | 35 (73) | 425 (65) |
| Age at onset (years), median (IQR) | 54.0 (46.0–67.0) | 49 (36–60) |
| Anti-Jo1 antibody positive | 17 (35) | 541 (83) |
| ILD | 47 (98) | 441 (68) |
| Raynaud’s phenomenon | 6 (13) | 252 (39) |
| Malignancy | 6 (13) | 21 (3) |
| Muscle weakness | 25 (52) | 549 (85) |
| Skin involvement, n (%) | ||
| Gottron’s sign | 35 (73) | 141 (22) |
| Heliotrope rash | 9 (19) | 90 (14) |
| Mechanic’s hands | 31 (65) | 200 (31) |
| Nailfold erythema | 19 (40) | 110 (17) |
| Shawl sign | 10 (21) | 18 (3) |
| V-neck sign | 6 (13) | 28 (4) |
| Calcification | 0 (0) | 13 (2) |
| Skin ulcer | 0 (0) | 8 (1) |
ILD Interstitial lung disease, IQR Interquartile range