TABLE 1.

Parameters of the model (Eqs. 1–3)

Parameter	Value	Unit
Leak flux coefficient Pl	0.00253	s−1
Channel flux coefficient Pc	3.9637	s−1
Capacity of endogenous pumps Pmax	Varied	μM s−1
Dissociation constant of endogenous pumps K	0.08892	μM
Capacity of additional pumps P1max	Varied	μM s−1
Dissociation constant of additional pumps K1	Varied	μM
Effective volume ratio νr = VER/Vcyt	0.185
Effective volume ratio νm = Vm/Vcyt	0.1
Effective diffusion coefficient D of Ca2+	40	μm2 s−1
Uniporter capacity Vmax(1)	9.0	μM s−1
Uniporter half maximum value Kd	4.5	μM
Na+-Ca2+-exchanger capacity Vmax(2)	9.0	μM s−1
Averaged total concentration of Ca2+CT	Varied	μM
Na+-Ca2+-exchanger half maximum value for Ca2+Km	3.0	μM
Na+-Ca2+-exchanger half maximum value for Na+KNa	5.0	mM
Cytosolic Na+ concentration Na	10.0	mM
β0(I)	0.8 μM/I
β1	0.36036	μM
β2	0.29952	μM
ɛ	0.15	s
Concentration of IP3I	Varied	μM