TABLE 3.

Results for model protein with heuristic and partly numerical estimates of reaction probability

	Heuristic		Partly numerical
wt ctl?	No	Yes	No	Yes
tstep(s)	7.69 × 10−6	8.85 × 10−6	7.68 × 10−6	8.83 × 10−6
	1.94 × 105	1.48 × 105	1.37 × 105	1.33 × 105
Ntrials	200,000	200,000	200,000	200,000
CPU(h)	82.8	73.0	58.4	65.3
EB	4.95 × 10−6	8.66 × 10−6	5.48 × 10−6	8.52 × 10−6
VarB	6.41 × 10−8	4.06 × 10−9	4.92 × 10−8	3.40 × 10−9
k(M−1s−1)	1.05 × 105	1.83 × 105	1.16 × 105	1.80 × 105
Δk(M−1s−1)	2.35 × 104	5.91 × 103	2.06 × 104	5.41 × 103
tmethod(h)	1667.3	30.4	735.3	23.5