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(a) As in Slepoy's model (Slepoy et al., 2001), subunits were healthy monomers (light gray spheres) aggregating with misfolded monomers (dark gray hexagons); (b), subunits are hexagonal intermediates (light gray/dark gray) aggregating with misfolded hexagonal structures (medium gray/dark gray). In both cases, the aggregation process and kinetics ought to be, and indeed are, similar.
