TABLE 5.

Probability of appearance of different channels in E. coli IOM and egg lecithin membranes under different conditions

		Probability (%)
				30 mol%
		0 mol %		Cholesterol	Ergosterol
Bilayer	Channel type	15°C	25°C	25°C	25°C
[AmB] M:		10−4	10−4*	10−5
E. coli IOM	I	nob	2.09	0.62
	II	2.19	1.92	0.19
	III	3.44	0.31	0.51
	IV	5.49	0.62	11.19
	V	nob	nob	0.17
	VI	nob	1.72	0.09
[AmB] M:		10−4	10−4	10−5	10−5†
Egg lecithin	I	0.15	nob	0.59	6.98
	II	3.70	0.43	0.26	12.23
	III	3.94	1.53	0.08	6.88
	IV	nob	0.13	4.06	1.37
	V	0.68	nob	1.81	0.16
	VI	nob	nob	0.93	0.09

nob, not observed.

^*Incorporation of AmB into the lipid chloroform mixture.

^†Incorporation of AmB into the membrane patch external solution.