TABLE 5.
Anti-LOS AFCs elicited in different tissues of mice by dLOS-CRM conjugate
| Routea | Antibody class | No. of AFCs/106 lymphoid cellsb
|
|||||
|---|---|---|---|---|---|---|---|
| NALT | NP | Spleen | Lung | CLN | PP | ||
| i.n. | IgA | 32b | 204 | 12 | 57 | 8 | 20 |
| IgG | 12 | 12 | 10 | 8 | 58 | 0 | |
| IgM | 2 | 2 | 28 | 0 | 117 | 8 | |
| s.c. | IgA | 0 | 0 | 0 | 0 | 0 | 0 |
| IgG | 0 | 4 | 218 | 4 | 184 | 0 | |
| IgM | 0 | 0 | 24 | 0 | 8 | 0 | |
| Naïve control | IgA | 0 | 0 | 0 | 0 | 0 | 0 |
| IgG | 0 | 0 | 0 | 0 | 0 | 0 | |
| IgM | 0 | 0 | 0 | 0 | 0 | 0 | |
a
See Table 4, footnote a.
b
The average number of AFCs per 106 lymphoid cells from two experiments. The lymphoid cells were collected from eight mice.