TABLE 2.

Detergent concentration sensitivity of different thermodynamic parameters

Detergent	dΔG° (kJ mol−1) dLog([Detergent]micellar)	dΔH° (kJ mol−1) dLog([Detergent]micellar)	−dTΔS° (kJ mol−1) dLog([Detergent]micellar)
C12Sulfate	−3.79 ± 0.57	13.7 ± 4.0	−17.5 ± 4.5
C12DAO	−7.27 ± 0.86	5.1 ± 1.8	−12.8 ± 2.2
Simple model	−5.74	0.0	−5.74

The sensitivity of the various parameters to the logarithm of the micellar detergent concentration was determined from the slopes of the different lines shown in Fig. 3. The simple model, described in the text, represents the values expected for a detergent that is able to form an ideal solution dissolving the peptide monomers and dimers entirely and exclusively in the micellar phase; this is fixed as –5.74 kJ mol and entirely entropic.