TABLE 3.
DOTAP/DNA charge ratio | Donor/Acceptor pair | [DNA] (μM) | [Donor] (μM) | [DOTAP] (M) | Equation for iDA(t) | Encapsulation efficiency (%)* |
---|---|---|---|---|---|---|
4 | BOBO-1/BODIPY-PC | 0.020 | 1.10 | 3.2 × 10−4 | 4 | 100 |
2 | BOBO-1/BODIPY-PC | 0.020 | 1.70 | 2.4 × 10−4 | 4 | 80 |
0.5 | BOBO-1/BODIPY-PC | 0.020 | 1.70 | 6.1 × 10−5 | 4 | 50 |
0.5 | DPH-PC/EtBr | 0.003 | 0.08 | 7.6 × 10−6 | 5 | 12 |
0.5 | BODIPY-PC/EtBr | 0.020 | 0.08 | 6.1 × 10−5 | 5 | 10 |
Fixed for the first experiment (from which d = 27 Å was recovered), and optimized for all others (assuming d = 27 Å, fixed).