Table 1.

sgRNAs

name	direction	location	protospacer sequence
sgRNA1	antisense	exon 14	5’-CGGGCCCACUGGCGUUCUGG-3'
sgRNA2	antisense	exon 14	5’-AUGAGGCUUGUGUUCAUACG-3'
sgRNA3	antisense	upstream exon 14	5’-AUGGUCUCUAAGGGACGGCU-3’
sgRNA4	sense	downstream exon 14	5’-AAGUGCAAGCCGAUGGGCGU-3’