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Binding isotherms for lipoplexes formed with natural DNA molecules. Lipid:DNA charge ratio was 2:1 for all the curves. The DNA concentration was 2 μM, except for the Dickerson dodecamer, included for comparison, for which it was 3 μM. ▪, Dickerson dodecamer; ○, herring sperm DNA; and □, λ-phage DNA. Curve for Dickerson dodecamer is obtained from fitting, others are guides to the eye.
